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This metabolite includes a PDE selectivity profile much like sildenafil and an in vitro potency for PDE5 around fifty% with the guardian drug. Plasma concentrations of this metabolite are approximately 40% of These noticed for sildenafil, so the metabolite accounts for about 20% of sildenafil's pharmacologic outcomes.

The following adverse reactions are identified for the duration of article approval use of VIAGRA. Because these reactions are reported voluntarily from the populace of unsure dimensions, It isn't generally possible to reliably estimate their frequency or set up a causal relationship to drug publicity.

Denne potensmedisinen skal kun brukes av personen den er foreskrevet til, og du bør derfor ikke gi medisinen til noen andre, selv om de kanskje har de samme symptomene på ereksjonssvikt som det du har. Dette legemidlet vil bare hjelpe deg med å få ereksjon hvis du er seksuelt stimulert.

VIAGRA is usually taken with or devoid of foods. If you're taking VIAGRA following a superior Body fat meal (such as a cheeseburger and french fries), VIAGRA might just take somewhat for a longer period to get started on Performing

Retain sildenafil out of the achieve of kids. If you retain sildenafil oral liquid within a fridge, Ensure that you keep it far from small children who also use the refrigerator.

Explain to all your healthcare suppliers you acquire VIAGRA. If you need unexpected emergency healthcare take care of a coronary heart issue, It's going to be significant on your healthcare company to understand if you previous took VIAGRA.

an erection that will not disappear (priapism). When you have an erection that lasts a lot more than 4 several hours, get clinical help without delay. If It's not at all dealt with straight away, priapism can permanently harm your penis.

20 topics obtained VIAGRA fifty mg, but only 19 subjects been given matching placebo. 1 affected person discontinued the research prematurely because more info of an adverse function of hypotension adhering to dosing with VIAGRA fifty mg. This client had been using minoxidil, a potent vasodilator, in the study.

Fortell din fastlege om dine plager dersom du ikke allerede har gjort det. Snakk med din fastlege fileør du tar Viagra Reseptfri, dersom du: 

Sexual activity can put an extra strain on the coronary heart, especially if your heart is currently weak from a heart assault or cardiovascular disease. Check with your health care provider In case your coronary heart is healthy ample to manage the additional pressure of having sexual intercourse.

Legemidlet skal ikke tas sammen med grapefrukt eller grapefruktjuice da dette kan gi angina og hjerteinfarkt. Medisinen skal heller ikke tas samtidig som andre orale eller lokale behandlinger mot erektil dysfunksjon.

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Though there have been no intense adverse gatherings perhaps linked to hypertension described On this research, one matter reported moderate vasodilatation immediately after both of those VIAGRA fifty mg and a hundred mg. There have been no episodes of syncope claimed in this study.

Viagra experienced no impact on saquinavir pharmacokinetics. A more robust CYP3A4 inhibitor like ketoconazole or itraconazole could be predicted to possess higher effect than that witnessed with saquinavir. Populace pharmacokinetic info from sufferers in medical trials also indicated a reduction in sildenafil clearance when it had been co-administered with CYP3A4 inhibitors (such as ketoconazole, erythromycin, or cimetidine) [see DOSAGE AND ADMINISTRATION and DRUG INTERACTIONS].